Do synactors have a sense of humour?

In games like Saints Row: the Third (developer: Volition, 2011) much of the synactors' humour comes from the pre-scripted little asides or interjections either from NPCs or from the player's character. There is a very nice joke in Saints Row: the Third that comes from falling through craft debris that keeps on coming and coming. The player's character comments on the unbelievability of the situation with the endless debris showing no sign of being exhausted. Its a nice joke because it is likely that the player notices the absurdity but understands they must go along with it and understands why the designers do such a thing in designing this particular challenge.

Jokes in Portal (better than in Portal 2).